Virus replication-independent expression of CCL3 and CXCL10 in HSV-1-infected human primary macrophages. Human macrophages were infected with HSV-1 (KOS, MOI of 1) or equivalent amount of UV-inactivated virus. A and B) After 6 hours of infection total RNA was harvested and expression of CCL3 and CXCL10 evaluated by RT-qPCR. Data depicted represent mean +/− SD of three independent donors from one of two experiments showing similar results. *, p<0.05 and **, p<0.01 (t-test).