| |
Patient 1
|
Patient 2
|
Patient 3
|
|---|
|
Family history available
|
No
|
Yes
|
No
|
|
Age at the time of the study
|
4 years
|
21 months
|
16 months
|
|
Age at onset
|
3 years
|
17 months
|
16 month
|
|
Fever
|
Yes
|
Yes
|
Yes
|
|
Hepatomegaly
|
4 cm
|
5 cm
|
2.5 cm
|
|
Splenomegaly
|
2 cm
|
3 cm
|
1 cm
|
|
White blood cells (×109/L)
|
11.6
|
6.36
|
3.03
|
|
Neutrophils (×109/L)
|
1.61
|
3.915
|
0.56
|
|
Hemoglobin (g/dL)
|
8.1
|
9.6
|
7.5
|
|
Platelets (×109/L)
|
95
|
56
|
30
|
|
LDH (IU/L)
|
449
|
1,693
|
1,698
|
|
AST (IU/L)
|
88
|
122
|
453
|
|
ALT (IU/L)
|
31
|
25
|
255
|
|
Ferritin (μg/L)
|
1,276
|
26,282
|
11,129
|
|
sIL-2R (U/mL)
|
3,162
|
2,880
|
14,334
|
|
IgG (mg/dL)
|
1,821
|
806
|
423
|
|
IgA (mg/dL)
|
302
|
124
|
32
|
|
IgM (mg/dL)
|
1,843
|
40
|
18
|
|
Whole blood EBV-DNA (copies/mL)
|
140,000
|
5,700
|
1,400,000
|
- LDH, lactate dehydrogenase; AST, aspartate amino transferase; ALT, alanine amino transferase, sIL-2R, soluble interleukin-2 receptor; NA: not available.
