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Figure 2 | Herpesviridae

Figure 2

From: Deciphering the role of Epstein-Barr virus in the pathogenesis of T and NK cell lymphoproliferations

Figure 2

Patterns of latent viral gene expression in EBV-associated tumours. Schematic illustrating major patterns of EBV gene expression observed in different virus:host interactions; non-coding RNAs and micro-RNAs are indicated in green type, nuclear proteins in black type, and membrane proteins in blue type. Latency 0, sometimes referred to as 'in vivo latency, is the type of latency observed in non-dividing circulating memory B cells of healthy carriers; it is possible that the majority of these cells express no viral genes at all, but that a minority may express non-coding RNAs. Latency I was originally identified in Burkitt' lymphoma, Latency II in nasopharyngeal carcinoma and Hodgkin's lymphoma, and Latency III in post-transplant lymphoproliferative disease.

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