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Figure 3 | Herpesviridae

Figure 3

From: Circulating herpes simplex type 1 (HSV-1)-specific CD8+T cells do not access HSV-1 latently infected trigeminal ganglia

Figure 3

Adoptively transferred gB-specific CD8+ T cells are excluded from HSV-1-infected TG during stable latency. CD8+ T cells were isolated from 30 dpi gBT I.1 (CD45.2) spleens and 106 cells were intravenously (i.v.) injected into latently infected wild-type mice (CD45.1). At indicated times after transfer, spleens, blood, and TG were harvested and stained for CD8¿, CD45, CD45.1, CD45.2, and gB-specific T cell receptor. Data represent the percentage of gB-specific cells that are CD45.1+ (endogenous). Data shown are the means and standard errors for 3 mice at each time point.

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