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Table 2 CD8+ T lymphocytes from HLA-B8+ donors frequently recognize the latent membrane protein 2 of Epstein Barr virus.

From: Cytolytic T lymphocytes from HLA-B8+donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus

Donor DCs only DC + LMP2345-352 DC + EBNA3A325-333
  vvTK- vvLMP2 vvTK- vvLMP2 vvTK- vvEBNA3A
#1 0 ± 0* 0 ± 0 0 ± 0 27.5 ± 1.5 10 ± 7 27 ± 0
#2 12 ± 1 8.5 ± 1.5 7.5 ± 0.5 19 ± 3 17 ± 0 30 ± 5
#3 14 ± 1 0.5 ± 0.5 1 ± 0 27.5 ± 3.5 7.5 ± 0.5 24 ± 3
#4 105 ± 15 37.5 ± 2.5 25.5 ± 9.5 70 ± 6 26 ± 1 79 ± 11
#5 8.5 ± 0.5 6 ± 3 1.5 ± 1.5 10.5 ± 0.5 9 ± 1 13 ± 1
#6 232.5 ± 8.5 230.5 ± 3.5 305 ± 27 581.5 ± 58.5 115 ± 5 205 ± 24
#7 5 ± 3 5.5 ± 2.5 3.5 ± 1.5 16 ± 2 10 ± 1 19 ± 1
#8 1 ± 1 2 ± 1 0 ± 0 6 ± 1 7 ± 1 60 ± 5
#9 27.5 ± 3.5 5 ± 1 3.5 ± 0.5 10.5 ± 2.5 37.5 ± 7.5 52 ± 2
#10 13 ± 2 27 ± 7 14 ± 1 74 ± 9 15 ± 3 68 ± 7
#11 25 ± 11 28 ± 6 25 ± 5 85 ± 21 23 ± 2 121.5 ± 13.5
  1. * spot forming cells (SFC)/5 × 104 cells. HLA-B8+ CD8+ T cells were stimulated for one week with dendritic cells pulsed with no peptide, LMP2345-352 or EBNA3A325-333 and then analyzed in ELISPOT assays against vvTK-, vvLMP2 and vvEBNA3A infected DCs. Specific responses as judged by the criterion of 10 spots over background and at least a 1.5 ratio of vvLMP2 to vvTK-stimulated spots are highlighted in bold.