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Table 1 Predicted HLA-B8 binding peptides derived from LMP2.

From: Cytolytic T lymphocytes from HLA-B8+donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus

LMP2 sequence

Amino acid sequence

SYFPEITHI rank/score*

BIMAS rank/value*

PAProC C-terminal cleavage prediction by version I or II

NetChop C-terminal cleavage prediction by version 2.0

172-179

AAAQRKLL

38/22

18/16.0

+/+

-

234-242

AYRRRWRRL

19/24

29/8.0

+/+

+

345-352

CPLSKILL

18/26

28/16.0

-/+

-

347-355

LSKILLARL

39/20

39/4.0

+/+

+

350-357

ILLARLFL

28/25

38/8.0

+/-

-

352-360

LARLFLYAL

29/22

19/16.0

-/+

+

  1. * Separate predictions were performed for octamers (X8) and nonamers (X9). Therefore, each rank can appear twice. Predicted scores or values for the two MHC ligand prediction programs SYFPEITHI and BIMAS as well as the proteasomal cleavage prediction programs PAProC and NetChop are shown.