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Figure 2 | Herpesviridae

Figure 2

From: Cytolytic T lymphocytes from HLA-B8+donors frequently recognize the Hodgkin's lymphoma associated latent membrane protein 2 of Epstein Barr virus

Figure 2

Frequency of LMP2 345-352 and EBNA3A 325-333 specific CD8+T cells in whole blood. Whole blood of three representative of six HLA-B8 positive donors was stimulated with medium, PHA or the EBNA3A325-333, LMP2345-352, LMP2347-355 peptides. CD69 up-regulation and intracellular IFN-γ production was measured by flow cytometry after gating on living CD8+ T cells. The indicated percentages represent CD69+/IFN-γ+ (upper number) and CD69+/INF-γ- (lower number) populations.

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