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Table 2 Comparisons of HCMV immunoreactivity between nonneoplatic breast tissue from known cancer patients and non-neoplastic breast tissue from breast reduction mammoplasty normal conrols.

From: Detection of human cytomegalovirus in normal and neoplastic breast epithelium

  Tumor Control (N = 21) Normal Control (N = 38) p of Chi-Square test
  N (examined) + N (examined) +  
   n %   n %  
IE 13 12 92 27 17 63 0.0678*
E/L 15 11 73 28 6 21 0.0009
L 13 10 77 28 11 39 0.0249
No Ab 9 0 0 20 0 0 --
CD34 6 0 0 9 0 0 --
Actin 8 0 0 29 0 0 --
  1. * Two-sided Fisher's exact test
  2. Specific immunoreactivity to HCMV E/L antigens was significantly higher in nonneoplastic breast from breast cancer cases than from breast reduction mammoplasty controls. Immunoreactivity to the HCMV late (L) antigen was also significantly higher in breast cancer than normal breast.