Table 1 Pyk2 binding partners in pUS28-expressing RSMC
From: HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase
CATEGORY | PROTEIN(S) IDENTIFIED |
|---|---|
Cytoskeleton Structure and Dynamics | β-actin, α1-actin, F-actin capping proteins-α1, -α2*, and -β, Gelsolin [51, 72, 88, 89], Myosin-9, -10, -11, Myosin light chain-6, Tropomodulin-3[72], Tropomyosin-α1, α3, α4 -β [72, 90, 91], Tubulin-β-2C, Vimentin [92] |
Signal Transduction | Calmodulin [30, 50], G-protein subunit β5 [93], KSR-2* [53, 94], Rhophilin-2* [95], Trio* [52, 96], TFG [54] |
Inflammation and Immunity | Immunoglobulin lambda light chain [97], NFκB p105 |
Cellular Proliferation |