Tegument protein control of latent herpesvirus establishment and animation

Herpesviridae

Table 1 Cells that support the different types of human herpesvirus infections.

Family	Virus	Productive (Lytic) Replication	Site of Latency
α	HSV-1	Epithelial and keratinocyte	Neuron
	HSV-2	Epithelial and keratinocyte	Neuron
	VZV	Epithelial, keratinocyte, T cell, sebocyte, monocyte, endothelial, Langerhans and PBMC	Neuron
β	HCMV	Macrophage, dendritic, endothelial, smooth muscle, epithelial and fibroblast	CD34+ HSC, monocyte
	HHV-6	T cell	BMP
	HHV-7	T cell	T cell
γ	EBV	B cell and epithelial	B cell
	KSHV	Lymphocyte	B cell

Common cell types in which the human herpesviruses, grouped by family, initiate productive lytic infection or establish latency are listed. PBMC, peripheral blood mononuclear cells. HSC, hematopoietic stem cell. BMP, bone marrow progenitor.