Herpesviridae

Table 1 Effects of maribavir on the relative levels of autophosphorylation of the wild type and mutant UL97 proteins.

From: The effects of maribavir on the autophosphorylation of ganciclovir resistant mutants of the cytomegalovirus UL97 protein

Ul97 species	% autophosphorylation
	No Maribavir	Plus Maribavir
Wild type	100	4.5 ± 2.0
K355Q	1.0 ± 0.9	0.5 ± 0.8
L397R	7.8 ± 3.3	7.8 ± 4.5
D456A	104.0 ± 4.0	5.0 ± 1.0
M460V	86 ± 2.0	3.9 ± 2.0
N461G	8.0 ± 1.8	4.2 ± 2.0
H520Q	103.5 ± 3.5	3.8 ± 1.5
A594T	107.0 ± 5.0	2.5 ± 2.5
L595F	100.0 ± 8.0	5.0 ± 1.0
H662L	102.5 ± 4.5	3.0 ± 1.5
V665I	100.5 ± 2.0	3.0 ± 1.5

The data are normalised relative to wild type and show the mean and standard deviation of triplicate analysis.

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